This thread is pretty old, however, I have this issue as of 2016-06. Is there anything known about it? Fixes/announcements thereof? Every third to fifth game, I desync a few secs for every five mins of gameplay (no AMD components, ping is constant at 30-35 ms, no matter whether the "particular" game shows desync or not. I even have desync'd games just for the next to work fine without any change, not even restarting the client).
It's just that I'd rather know whether this is "on the radar" before spending a lot of money and/or time on this game.